- CAS
- Purity
- 59-48-3
- 99%
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Quality products?make an important contribution to long-term revenue and profitability. Excellent chemical plant bulk supply Oxindole 59-48-3
Oxindole is considered as indole analogue, which shows pharmacological activity.
methyl (2-nitrophenyl)acetate
indole
2-oxoindole
2-aminophenethyl alcohol
2-aminophenylacetic acid methyl ester
| Conditions | Yield |
|---|---|
|
With
sodium tetrahydroborate;
In
tetrahydrofuran; water;
at 20 ℃;
for 12h;
chemoselective reaction;
Sonication;
|
C29 H37 NO6
2-oxoindole
prednisolon
| Conditions | Yield |
|---|---|
|
With
water;
at 37 ℃;
pH=7.4 - 8;
Kinetics;
|
The CAS number of Oxindole is 59-48-3.
More information of Oxindole 59-48-3 are:
|
CAS?Number |
59-48-3 |
|
Density |
1.198 g/cm3 |
|
Melting Point |
123-128 °C(lit.) |
|
Boiling Point |
312.7 °C at 760 mmHg |
|
Flash Point |
177.8 °C |
|
Vapor Pressure |
0.000521mmHg at 25°C |
|
Refractive Index |
1.5282 (estimate) |
|
HS CODE |
2933.99 |
|
PSA |
29.10000 |
|
LogP |
1.31920 |
|
Pka |
14.77±0.20(Predicted) |
Synonyms?for?Oxindole 59-48-3:2-Indolinone(7CI,8CI);Oxindole (6CI);1,3-Dihydro-2H-indol-2-one;1,3-Dihydroindol-2-one;2-Indolone;2-Oxindole;2-Oxo-2,3-dihydroindole;2-Oxoindole;2-Oxoindoline;Indol-2(3H)-one;Indoline-2-one;NSC 274863;Oxindol;
The chemical formula of ?Oxindole is?C8H7NO which containing 8 Carbon atoms,7 Hydrogen atoms,1 Nitrogen atoms and 1 Oxygen atoms,and the molecular weight of??Oxindole?is 133.15.
Oxindole, a bicyclic monoterpene alkaloid, exhibits a simple, viable yet challenging synthesis approach, though it undoubtedly forms the core of a class of biologically important compounds. Most often found naturally, being a tryptophan derivative, it is produced in the human body in the gut by ‘normal flora’ bacteria as well, hence getting the name- ‘Human metabolite of Indole’. Many derivatives of oxindole are also obtained from habitual plant-based sources, which later became an ingredient in several traditional or ‘folk’ medicinal practices. Amongst derivaices containing oxindole core, one of the simplest subclasses of oxindoles is 3-alkenyl-oxindoles, nearly all of them are obtained from natural sources. The first known indigenously occurring 3-alkenyl-oxindoles were extracted and isolated from the subterranean plant stem or ‘rhizomes’ of the perennial Cimicifuga dahurica plant, from the Cimicifuga dry rootstock species, around half a century ago, in the year 1978. Other derivatives in traditional medical use, till date, include 2-indolinone type of oxindoles, used extensively as antipyretic agents.
InChI:InChI=1/C8H7NO/c10-8-5-6-3-1-2-4-7(6)9-8/h1-4H,5H2,(H,9,10)
Relevant articles related to Oxindole:
|
Article |
Source |
|
Synthesis, Docking, and Bioavailability of 2′-Oxo-3-phenylspiro[cyclopropane-1,3′-indoline]-2,2-dicarbonitriles as Antibacterial Agents In Silico |
Avula, Vijay Kumar Reddy,Chintha, Venkata Ramaiah,Vallela, Swetha,Anireddy, Jaya Shree,Chamarthi, Naga Raju,Wudayagiri, Rajendra , p. 209 - 217 (2019) |
|
Kinetics and mechanism of meso-tetraphenylporphyriniron(III) chloride catalyzed oxidation of indole by peroxomonosulphate |
Kungumathilagam,Karunakaran , p. 4311 - 4314 (2013) |
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