- CAS
- Purity
- 537-55-3
- 99%
Location：Home > Pharmaceutical
High Quality Chinese Factory supply 537-55-3 N-Acetyl-L-tyrosine
- Molecular Formula: C11H13NO4
- Molecular Weight: 223.229
- Appearance/Colour: solid
- Vapor Pressure: 4.07E-12mmHg at 25°C
- Melting Point: 149-152 °C(lit.)
- Refractive Index: 1.4960 (estimate)
- Boiling Point: 531.3 °C at 760 mmHg
- PKA: 3.15±0.10(Predicted)
- Flash Point: 275.1 °C
- PSA： 86.63000
- Density: 1.304 g/cm3
- LogP: 0.91490
N-Acetyl-L-tyrosine(Cas 537-55-3) Usage
|
benefits |
N-Acetyl-L-Tyrosine (NALT) plays a necessary part in the synthesis of dopamine and other hormones in your body. It can boost levels of the neurotransmitters dopamine, norepinephrine and epinephrine. It helps to support higher levels of focus and cognitive function. It can increase working memory and feelings of well-being. |
|
Side effects |
L-tyrosine gets the generally regarded as safe (GRAS) stamp of approval from the FDA. Some side effects of N-Acetyl-L-tyrosine (NALT) include nausea, headache, fatigue, and heartburn. It can be safely taken for extended periods of time. |
|
Definition |
ChEBI: N-acetyl-L-tyrosine is an N-acetyltyrosine in which the chiral centre has L configuration. It has a role as an EC 2.1.1.4 (acetylserotonin O-methyltransferase) inhibitor, a biomarker and a human urinary metabolite. It is a N-acyl-L-tyrosine and a N-acetyltyrosine. It is a conjugate acid of a N-acetyl-L-tyrosinate. |
|
Application |
N-Acetyl-L-tyrosine is a tyrosine derivative with a chemical structure similar to that of an amino acid. It is used as a model system in biochemistry and molecular biology to study the transfer reactions of tyrosine, which are important for energy metabolism, protein synthesis, and metal chelation. N-acetyl-L-tyrosine may be used as an indicator to distinguish neurosyphilis patients from syphilis/non-neurosyphilis patients. N-acetyl-L-tyrosine is a precursor of the essential neurotransmitter dopamine. |
InChI:InChI=1/C11H13NO4/c1-7(13)12-10(11(15)16)6-8-2-4-9(14)5-3-8/h2-5,10,14H,6H2,1H3,(H,12,13)(H,15,16)/p-1/t10-/m0/s1
537-55-3 Relevant articles
Unusual Enhancement of Protease Activity in Organic Solvents by Amines
Yamamoto, Yasuhito,Kise, Hideo
, p. 1821 - 1824 (1993)
The catalytic activities of subtilisin B...
Fluorescence Spectroscopic Study of α-Chymotrypsin as Relevant to Catalytic Activity in Aqueous-Organic Media
Tomiuchi, Yoshimasa,Kijima, Tatsurou,Kise, Hideo
, p. 1176 - 1181 (1993)
The effects of the composition of aqueou...
Effect of dioxane on the binding of competitive inhibitor proflavin and catalytic activity of bovine pancreatic α-chymotrypsin
Sirotkin,Mukhametzyanov,Karmanova
, p. 1160 - 1164 (2007)
The binding of competitive inhibitor pro...
Structure-activity relationship studies of dipeptide-based hepsin inhibitors with Arg bioisosteres
Kwon, Hongmok,Ha, Hyunsoo,Jeon, Hayoung,Jang, Jaebong,Son, Sang-Hyun,Lee, Kiho,Park, Song-Kyu,Byun, Youngjoo
supporting information, (2020/12/25)
Hepsin is a type II transmembrane serine...
GRANZYME B DIRECTED IMAGING AND THERAPY
-
Page/Page column 82; 98, (2019/09/04)
Provided herein are heterocyclic compoun...
Photoinduced electron transfer-promoted debenzylation of phenylalanine and tyrosine derivatives using dicyanoarene
Yamawaki, Mugen,Okita, Yoshiki,Yamamoto, Takashi,Morita, Toshio,Yoshimi, Yasuharu
, p. 7239 - 7244 (2017/11/20)
Photoinduced debenzylations of phenylala...
Radical arylation of tyrosine residues in peptides
Fehler, Stefanie K.,Pratsch, Gerald,?streicher, Christiane,Fürst, Michael C.D.,Pischetsrieder, Monika,Heinrich, Markus R.
supporting information, p. 7888 - 7893 (2016/11/17)
The radical arylation of the phenolic si...
537-55-3 Process route
-
-
108-24-7
acetic anhydride
-
-
60-18-4,18875-48-4,25619-78-7,30704-25-7
L-tyrosine
-
-
537-55-3
N-acetyl-L-tyrosine
Conditions
| Conditions | Yield |
|---|---|
|
In
water;
for 4 - 5h;
Heating / reflux;
|
71%
|
|
In
water;
for 4 - 5h;
Heating / reflux;
|
71%
|
|
With
sodium hydroxide;
|
|
|
With
water;
|
|
|
In
water;
|
|
|
In
water;
at 90 - 100 ℃;
for 2h;
|
|
|
In
water;
at 90 - 95 ℃;
for 2h;
|
|
|
With
sodium hydrogencarbonate;
In
water;
at 0 - 20 ℃;
for 2h;
|
|
|
In
methanol;
at 40 ℃;
|
|
|
With
sodium hydroxide;
In
1,4-dioxane; water;
at 0 - 20 ℃;
|
|
|
With
sodium hydroxide;
In
water;
at 20 ℃;
pH=14;
|
-
-
2440-79-1
N-acetyl-L-tyrosine methyl ester
-
-
537-55-3
N-acetyl-L-tyrosine
Conditions
| Conditions | Yield |
|---|---|
|
With
lithium hydroxide;
In
tetrahydrofuran; water;
at 65 ℃;
for 3h;
|
84%
|
|
With
sodium hydroxide; ethanol;
|
|
|
N-acetyl-L-tyrosine methyl ester;
With
lithium hydroxide; water;
In
tetrahydrofuran;
at 60 ℃;
for 1h;
With
hydrogenchloride;
In
tetrahydrofuran; water;
at 20 ℃;
pH=4;
Reactivity;
|
|
|
N-acetyl-L-tyrosine methyl ester;
With
lithium hydroxide; water;
In
tetrahydrofuran;
at 60 ℃;
for 1h;
With
hydrogenchloride;
In
tetrahydrofuran; water;
at 20 ℃;
pH=4;
|
537-55-3 Upstream products
-
840-97-1
N-acetyl-L-tyrosine ethyl ester
-
2440-79-1
N-acetyl-L-tyrosine methyl ester
-
949-67-7
L-tyrosine ethyl ester
-
108-24-7
acetic anhydride
537-55-3 Downstream products
-
17355-24-7
(S)-N-acetyl-3-(4-methoxyphenyl)alanine methyl ester
-
2440-79-1
N-acetyl-L-tyrosine methyl ester
-
840-97-1
N-acetyl-L-tyrosine ethyl ester
-
20767-00-4
3.5-Dinitro-N -acetyl-L-tyrosin