Location:Home > Pharmaceutical

Trityl candesartan


  • CAS
  • Purity
  • 139481-72-4
  • 99%
Inquiry

Quality products?make an important contribution to long-term revenue and profitability. Manufacturer supply good quality Trityl candesartan 139481-72-4 with stock

1.What is the Trityl candesartan ?

Candesartan analog as angiotensin II antagonist.

trityl chloride
76-83-5

trityl chloride

candesartan
139481-59-7

candesartan

2-Ethoxy-1-[[2'-(N-triphenylmethyltetrazol-5-yl)-biphenyl-4-yl]methyl]benzimidazole-7-carboxylic acid
139481-72-4

2-Ethoxy-1-[[2'-(N-triphenylmethyltetrazol-5-yl)-biphenyl-4-yl]methyl]benzimidazole-7-carboxylic acid

Conditions
Conditions Yield
With triethylamine; In dichloromethane; at 15 - 23 ℃; for 3.5h; Temperature; Flow reactor; Large scale;
94%
With triethylamine; In acetone; at 55 - 60 ℃; for 4 - 8h; Product distribution / selectivity;
90%
With triethylamine; In acetone; at 55 - 60 ℃; Product distribution / selectivity;
90%
With triethylamine; In methyl iso-butyl ketone (MIBK); at 55 - 60 ℃; for 4 - 8h; Product distribution / selectivity;
89%
With triethylamine; In butanone; at 55 - 60 ℃; for 4 - 8h; Product distribution / selectivity;
88%
With triethylamine; In dichloromethane; at 25 - 30 ℃; for 2h; Heating / reflux;
83.8%
With triethylamine; In dichloromethane; at 20 ℃; for 2.5h;
53%
With triethylamine; In dichloromethane; at 0 - 20 ℃; for 19h;
52.3%
trityl chloride; candesartan; With triethylamine; In N,N-dimethyl-formamide; at 25 - 65 ℃;
With hydrogenchloride; In ethanol; N,N-dimethyl-formamide; pH=4.6;
With triethylamine; In dichloromethane; at 0 - 20 ℃; for 8h;
With triethylamine; In dichloromethane; at 25 - 35 ℃; for 3.75h;
With triethylamine; In dichloromethane; at 0 - 20 ℃; for 8h;
With triethylamine; In dichloromethane; at 25 - 35 ℃; for 20h; Solvent;
125.5 g
ethyl acetate-benzene

ethyl acetate-benzene

trityl chloride
76-83-5

trityl chloride

candesartan
139481-59-7

candesartan

2-Ethoxy-1-[[2'-(N-triphenylmethyltetrazol-5-yl)-biphenyl-4-yl]methyl]benzimidazole-7-carboxylic acid
139481-72-4

2-Ethoxy-1-[[2'-(N-triphenylmethyltetrazol-5-yl)-biphenyl-4-yl]methyl]benzimidazole-7-carboxylic acid

Conditions
Conditions Yield
With triethylamine; In dichloromethane;
66%

2.What is the CAS number for Trityl candesartan ?

The CAS number of Trityl candesartan is 139481-72-4.

More information of Trityl candesartan 139481-72-4 are:

CAS?Number

139481-72-4

Density

1.26 g/cm3

Melting Point

163-165 °C

Boiling Point

908.6 °C at 760 mmHg

Flash Point

503.3 °C

Vapor Pressure

0mmHg at 25°C

Refractive Index

1.677

HS CODE

2933990090

PSA

107.95000

LogP

8.34220

Pka

2.06±0.10(Predicted)

3.What are another words for Trityl candesartan ?

Synonyms?for?Trityl candesartan 139481-72-4:2-Ethoxy-1-[[2’-(2-Triphenylmethyl)-2H-Tetrazole-5-Yl](1,1’-Biphenyl)-4-Yl]-Methyl]Benzimidazole-7-Carboylicacid;

4.What is the molecular formula of Trityl candesartan?

The chemical formula of ?Trityl candesartan is?C43H34N6O3 which containing 43 Carbon atoms,34 Hydrogen atoms,6 Nitrogen atoms and 3 Oxygen atoms,and the molecular weight of??Trityl candesartan?is 682.781.

5.What is Trityl candesartan (139481-72-4) used for?

Trityl candesartan, also known as 2-Ethoxy-1-((2''-(1-trityl-1H-tetrazol-5-yl)-[1,1''-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-7-carboxylic Acid, is a chemical compound with off-white solid properties. It is a candesartan analog, which is an angiotensin II antagonist, and is primarily used in the preparation of the anti-hypertensive drug candesartan cilexetil.

InChI:InChI=1/C43H34N6O3/c1-2-52-42-44-38-24-14-23-37(41(50)51)39(38)48(42)29-30-25-27-31(28-26-30)35-21-12-13-22-36(35)40-45-46-47-49(40)43(32-15-6-3-7-16-32,33-17-8-4-9-18-33)34-19-10-5-11-20-34/h3-28H,2,29H2,1H3,(H,50,51)

Relevant articles related to Trityl candesartan:

Article

Source

Benzimidazole compound and medical application thereof

-

Paragraph 0038-0041, (2021/05/05)

METHOD FOR PREPARING TRITYL CANDESARTAN

-

Paragraph 0031-0034, (2018/06/15)

6.Buy Trityl candesartan with the best price .

Hangzhou Share Chemical Co., Ltd is a quality supplier of Trityl candesartan. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on Trityl candesartan 139481-72-4.

*Product Name
CAS
Purity
Quantity
Company name
*Email
*Other Description
*Code
Items marked with* are mandatory
Submit