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4-N-Boc-aminopiperidine


  • CAS
  • Purity
  • 73874-95-0
  • 99%
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1.What is the 4-N-Boc-aminopiperidine ?

Pharma building block.

tert-butyl (1-benzylpiperidin-4-yl)carbamate
73889-19-7

tert-butyl (1-benzylpiperidin-4-yl)carbamate

(piperidin-4-yl)carbamic acid tert-butyl ester
73874-95-0

(piperidin-4-yl)carbamic acid tert-butyl ester

Conditions
Conditions Yield
With hydrogen; palladium 10% on activated carbon; In methanol; for 12h;
99%
With hydrogen; palladium 10% on activated carbon; In methanol; for 12h;
99%
With hydrogen; palladium on activated charcoal; In methanol; for 18h; under 2585.74 Torr;
97%
With hydrogen; palladium on carbon; In methanol; at 20 ℃;
96%
With hydrogen; palladium on activated charcoal; In methanol; at 20 ℃;
95%
With hydrogenchloride; 10 wt% Pd(OH)2 on carbon; water; hydrogen; In methanol;
94%
With cyclohexene; palladium dihydroxide; In ethanol; for 3.5h; Heating;
92%
With palladium 10% on activated carbon; ammonium formate; In methanol; at 65 ℃; for 2h; Reflux;
85%
With formic acid; potassium hydroxide; In ethanol; at 70 ℃; for 1h;
81%
With hydrogen; palladium 10% on activated carbon; In ethanol; at 20 ℃; for 16h;
76%
With hydrogen; palladium 10% on activated carbon; In methanol; for 18h; under 2585.81 Torr;
With hydrogen; palladium 10% on activated carbon; In tetrahydrofuran; ethanol;
palladium-carbon; In ethanol;
palladium; In ethanol;
2.87 g (14.4 mmol, 91.4%)
palladium; In methanol;
palladium on charcoal; In methanol;
With sodium hydroxide; sodium chloride; ammonium formate; palladium on charcoal; In methanol; hexane; water;
With hydrogen; palladium 10% on activated carbon; In ethanol; at 20 ℃; for 24h;
With hydrogen; palladium 10% on activated carbon; In ethanol; at 40 ℃;
With palladium 10% on activated carbon; hydrogen; In ethanol;
With palladium 10% on activated carbon; hydrogen; In methanol; for 24h;
With acetic acid; palladium-carbon catalyst; In methanol;
With hydrogen; palladium 10% on activated carbon; In methanol; for 18h; under 2585.81 Torr;
C<sub>17</sub>H<sub>24</sub>N<sub>2</sub>O<sub>2</sub>

C17 H24 N2 O2

(piperidin-4-yl)carbamic acid tert-butyl ester
73874-95-0

(piperidin-4-yl)carbamic acid tert-butyl ester

Conditions
Conditions Yield
With palladium 10% on activated carbon; hydrogen; In methanol; at 70 ℃; for 4h; under 6000.6 - 7500.75 Torr; Reagent/catalyst; Temperature;
90.7%

2.What is the CAS number for 4-N-Boc-aminopiperidine ?

The CAS number of 4-N-Boc-aminopiperidine is 73874-95-0.

More information of 4-N-Boc-aminopiperidine 73874-95-0 are:

CAS?Number

73874-95-0

Density

1.02 g/cm3

Melting Point

162-166 °C

Boiling Point

304.8 °C at 760 mmHg

Flash Point

138.2 °C

Vapor Pressure

0.000854mmHg at 25°C

HS CODE

29339900

PSA

50.36000

LogP

1.98280

Pka

12.39±0.20(Predicted)

3.What are another words for 4-N-Boc-aminopiperidine ?

Synonyms?for?4-N-Boc-aminopiperidine 73874-95-0:4-N-Boc-amino-piperidine;4-(N-tert-Butoxycarbonylamino)piperidine;4-Boc-AminoPiperidine;4-tert-Butoxycarbonyl-aminopiperidine;4-(N-BOC-amino) piperidine;4-N-Boc-Amino Piperidine;4-(Boc-amino)piperidine;tert-butyl piperidin-4-ylcarbamate;4-(N-Boc-amino)piperidine;4-Boc-amino piperidine;4-Boc-aminopiperindine;4-N-(tert-Butoxycarbonyl)aminopiperidine;N-Boc-piperidin-4-amine;tert-butyl N-(3,4,5,6-tetrahydro-2H-pyridin-4-yl)carbamate;

4.What is the molecular formula of 4-N-Boc-aminopiperidine?

The chemical formula of ?4-N-Boc-aminopiperidine is?C10H20N2O2 which containing 10 Carbon atoms,20 Hydrogen atoms,2 Nitrogen atoms and 2 Oxygen atoms,and the molecular weight of??4-N-Boc-aminopiperidine?is 236.742.

5.What is 4-N-Boc-aminopiperidine (73874-95-0) used for?

4-(N-Boc-amino)piperidone may be used as a functionalization reagent for introduction of a primary and a tertiary amino group to poly(2-isopropyl-2-oxazoline. It can also be used as pharma building block. It is used in the synthesis of a piperidine-4-carboxamide CCR5 antagonist with potent anti-HIV 1-activity. It is an intermediate for the synthesis of various pharmaceutical and biologically active compounds, including inhibitors and therapeutic agents. It is used for the synthesis of diphenyl purine derivatives as peripherally selective cannabinoid receptor 1 Antagonists.

InChI:InChI=1/C10H20N2O2/c1-10(2,3)14-9(13)12-8-4-6-11-7-5-8/h8,11H,4-7H2,1-3H3,(H,12,13)/p+1

Relevant articles related to 4-N-Boc-aminopiperidine:

Article

Source

Substituted 2-thioxothiazolidin-4-one derivatives showed protective effects against diabetic cataract via inhibition of aldose reductase

Huang, Wanrong,Zhang, Yue,Liang, Xu,Yang, Lichun

, (2020/04/07)

Method for preparing 4-Boc-aminopiperidine

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Paragraph 0024; 0026; 0027; 0029; 0030; 0032; 0033; 0035, (2018/04/15)

6.Buy 4-N-Boc-aminopiperidine with the best price .

Hangzhou Share Chemical Co., Ltd is a quality supplier of 4-N-Boc-aminopiperidine. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on 4-N-Boc-aminopiperidine 73874-95-0.

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