- CAS
- Purity
- 230615-70-0
- 99%
Quality products?make an important contribution to long-term revenue and profitability. Factory Supply Industrial Grade 6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 7,8,9,10-tetrahydro-8-(trifluoroacetyl)- 230615-70-0 with Best Price
7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine is used to prepare varenicline, which is a smoking cessation. It is a Varenicline protected impurity.
1-(7,8-diamino-4,5-dihydro-1H-1,5-methanobenzo[d]azepin-3(2H)-yl)-2,2,2-trifluoroethanone
Glyoxal
1-(9,10-dihydro-6H-6,10-methanoazepino[4,5-g]quinoxaline-8(7H)-yl)-2,2,2,-trifluoroethanone
| Conditions | Yield |
|---|---|
|
With
Amberlite IRA 67;
In
tetrahydrofuran; water;
at 0 - 30 ℃;
Product distribution / selectivity;
|
95%
|
|
In
tetrahydrofuran; water;
at 25 - 60 ℃;
Product distribution / selectivity;
|
74.48%
|
|
In
water;
at 80 ℃;
|
|
|
With
sodium hydrogencarbonate;
In
water; toluene;
at 20 - 25 ℃;
for 0.5h;
Product distribution / selectivity;
|
|
|
In
water; acetonitrile;
|
|
|
In
water; acetonitrile;
Inert atmosphere;
|
1-(4,5-diamino-10-azatricyclo[6.3.1.02,7 ]dodeca-2,4,6-trien-10-yl)-2,2,2-trifluoroethanone
Glyoxal
1-(5,8,14-triazatetracyclo[10.3.1.02,11 .04,9 ]hexadeca-2,4,6,8,10-pentaen-4-yl)-2,2,2-trifluoroethanone
| Conditions | Yield |
|---|---|
|
With
Amberlite IRA 67;
In
tetrahydrofuran; water;
at 0 - 30 ℃;
|
95%
|
|
In
water; isopropyl alcohol;
at 0 - 20 ℃;
for 21h;
pH=6.9;
Product distribution / selectivity;
|
|
|
With
sodium hydroxide;
In
water; isopropyl alcohol;
at 0 - 20 ℃;
for 21h;
pH=9.8;
Product distribution / selectivity;
|
|
|
With
triethylamine;
In
methanol; water;
at 10 - 30 ℃;
for 1h;
|
|
|
In
tetrahydrofuran; water;
at 20 - 50 ℃;
|
The CAS number of 6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 7,8,9,10-tetrahydro-8-(trifluoroacetyl)- is 230615-70-0.
More information of 6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 7,8,9,10-tetrahydro-8-(trifluoroacetyl)- 230615-70-0 are:
|
CAS?Number |
230615-70-0 |
|
Density |
1.449 g/cm3 |
|
Melting Point |
164-166 °C |
|
Boiling Point |
491.9 °C at 760 mmHg |
|
Flash Point |
251.3 °C |
|
Vapor Pressure |
8.05E-10mmHg at 25°C |
|
Refractive Index |
1.604 |
|
HS CODE |
2933990090 |
|
PSA |
46.09000 |
|
LogP |
2.54310 |
|
Pka |
1.50±0.20(Predicted) |
Synonyms?for?6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 7,8,9,10-tetrahydro-8-(trifluoroacetyl)- 230615-70-0:6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine,7,8,9,10-tetrahydro-8-(trifluoroacetyl)- (9CI);
The chemical formula of ?6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 7,8,9,10-tetrahydro-8-(trifluoroacetyl)- is?C15 H12 F3 N3 O which containing 15 Carbon atoms,12 Hydrogen atoms,3 Fluorine atoms,3 Nitrogen atoms and 1 Oxygen atoms,and the molecular weight of??6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 7,8,9,10-tetrahydro-8-(trifluoroacetyl)-?is 307.275.
6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 7,8,9,10-tetrahydro-8-(trifluoroacetyl)is a chemical compound with a complex molecular structure. It is characterized by its unique arrangement of atoms and functional groups, which contribute to its specific properties and potential applications.
InChI:InChI=1/C15H12F3N3O/c16-15(17,18)14(22)21-6-8-3-9(7-21)11-5-13-12(4-10(8)11)19-1-2-20-13/h1-2,4-5,8-9H,3,6-7H2
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