- CAS
- Purity
- 11076-19-0
- 99%
Quality products?make an important contribution to long-term revenue and profitability. Manufacturer supply good quality BONGKREKIC ACID 11076-19-0 with stock
1.What is the BONGKREKIC ACID ?
Bongkrekic acid solution has been used as an adenine nucleotide translocator (ANT) inhibitor to find out a different approach for the inhibition of oxidative phosphorylation in intact T98G cells. It has also been used as an inhibitor of the permeabilization transition pore complex (PTPC) pore and a tool to explore the role of PTPC in induction of apoptosis.
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88304-12-5,88335-55-1
(2E,4Z,8Z,10E,14E)-(6R,17S)-17-(4-Carboxymethyl-6-oxo-3,6-dihydro-2H-pyran-2-yl)-6-methoxy-2,5-dimethyl-octadeca-2,4,8,10,14-pentaenoic acid
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11076-19-0
bongkrekic acid
Conditions
| Conditions | Yield |
|---|---|
|
With
potassium methanolate;
In
tetrahydrofuran; methanol;
at 0 ℃;
for 0.0833333h;
|
65%
|
-
-
C31 H44 O7
-
-
11076-19-0
bongkrekic acid
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-
60132-21-0
isobongkrekic acid
Conditions
| Conditions | Yield |
|---|---|
|
C31H44O7;
With
water; potassium hydroxide;
In
1,2-dimethoxyethane;
at 20 ℃;
for 8h;
With
hydrogenchloride;
In
1,2-dimethoxyethane; water;
optical yield given as %de;
Further stages;
|
35%
17% |
2.What is the CAS number for BONGKREKIC ACID ?
The CAS number of BONGKREKIC ACID is 11076-19-0.
More information of BONGKREKIC ACID 11076-19-0 are:
|
CAS?Number |
11076-19-0 |
|
Density |
1.114g/cm3 |
|
Melting Point |
50-60° |
|
Boiling Point |
715.1°Cat760mmHg |
|
Flash Point |
231°C |
|
Refractive Index |
1.545 |
|
PSA |
121.13000 |
|
LogP |
5.88560 |
|
Pka |
4.15±0.10(Predicted) |
3.What are another words for BONGKREKIC ACID ?
Synonyms?for?BONGKREKIC ACID 11076-19-0:2,4,8,10,14,18,20-Docosaheptaenedioicacid, 20-(carboxymethyl)-6-methoxy-2,5,17-trimethyl-,[R-[R*,S*-(E,Z,Z,E,E,Z,E)]]-; Bongkrekic acid (6CI,8CI)
4.What is the molecular formula of BONGKREKIC ACID?
The chemical formula of ?BONGKREKIC ACID is?C28H38 O7 which containing 28 Carbon atoms,38 Hydrogen atoms and 7 Oxygen atoms,and the molecular weight of??BONGKREKIC ACID?is 486.606.
5.What is BONGKREKIC ACID (11076-19-0) used for?
Bongkrekic acid (11076-19-0) is a p potent inhibitory ligand of the mitochondrial adenine nucleotide translocase (ANT).1?Inhibits mitochondrial permeability transition pore opening.2,3?Delivery of bongkrekic acid to the mitochondria prevents apoptosis in HeLa cells.4
InChI:InChI=1/C28H38O7/c1-21(15-18-24(19-26(29)30)20-27(31)32)13-11-9-7-5-6-8-10-12-14-25(35-4)22(2)16-17-23(3)28(33)34/h6,8-12,15-19,21,25H,5,7,13-14,20H2,1-4H3,(H,29,30)(H,31,32)(H,33,34)/b8-6+,11-9-,12-10+,18-15-,22-16-,23-17+,24-19+
Relevant articles related to BONGKREKIC ACID:
|
Article |
Source |
|
Efficient Total Synthesis of Bongkrekic Acid and Apoptosis Inhibitory Activity of Its Analogues |
Matsumoto, Kenji,Suyama, Masaki,Fujita, Satoshi,Moriwaki, Takuya,Sato, Yukiko,Aso, Yoshifumi,Muroshita, Satoshi,Matsuo, Hiroshi,Monda, Keishi,Okuda, Katsuhiro,Abe, Masato,Fukunaga, Hiroyuki,Kano, Arihiro,Shindo, Mitsuru , p. 11590 - 11602 (2015/08/03) |
|
Total synthesis of the anti-apoptotic agents Iso- And bongkrekic acids |
Francais, Antoine,Leyva, Antonio,Etxebarria-Jardi, Gorka,Ley, Steven V. supporting information; experimental part, p. 340 - 343 (2010/03/25) |
6.Buy BONGKREKIC ACID with the best price .
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